Electronic brachytherapy management of atypical fibroxanthoma: report of 8 lesions

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Electronic brachytherapy management of atypical fibroxanthoma: report of 8 lesions

PURPOSE To evaluate the suitability of treating atypical fibroxanthoma (AFX), an uncommon skin malignancy, with electronic brachytherapy. MATERIAL AND METHODS From Feb 2013 to Sep 2014, we were referred a total of 8 cases of AFX in 7 patients, all involving the scalp. All of them were treated with electronic brachytherapy 50 Kev radiations (Xoft Axxent®, Fremont, California). All lesions rece...

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Atypical Fibroxanthoma

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its association with ultraviolet radiation, not only from a clinical aspect, but also from a molecular aspect. Making a diagnosis of AFX is challenging, and it is important to differentiate it from squamous ce...

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Atypical fibroxanthoma†

Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic origin. AFX is a curable cutaneous disease and the diagnosis depends on knowledge of its clinical and histological features and combined immunohistochemistry markers. This study presents a case of a male patient, aged 90 years, presented with painless skin lesion in his ear. The lesion had been growing...

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Atypical Fibroxanthoma of the Eyelid

Atypical fibroxanthoma (AFX) is an uncommon, fibrohistiocytic tumor of the skin that occurs due to actinic damage in the elderly (1). AFX rarely affects eyelid (2). It appears as solitary nodule that smaller than 2 cm (3). Boynton was the first to describe a case of AFX involving the eyelid in the literature (2). Aggresive recurrence was reported in few AFX cases, despite the benign nature of t...

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Genomic analysis of atypical fibroxanthoma

Atypical fibroxanthoma (AFX), is a rare type of skin cancer affecting older individuals with sun damaged skin. Since there is limited genomic information about AFX, our study seeks to improve the understanding of AFX through whole-exome and RNA sequencing of 8 matched tumor-normal samples. AFX is a highly mutated malignancy with recurrent mutations in a number of genes, including COL11A1, ERBB4...

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ژورنال

عنوان ژورنال: Journal of Contemporary Brachytherapy

سال: 2017

ISSN: 1689-832X

DOI: 10.5114/jcb.2017.65454